Tag Archives: Depression

Insomnia treatment may help ease depression during menopause

Women going through menopause may have fewer symptoms of depression when they get treatment for insomnia than when they don’t, a recent experiment suggests. Researchers recruited 117 menopausal women with insomnia for the study and randomly assigned them to three groups. One group received cognitive behavior therapy (CBT). Another group received a component of CBT… Read More »

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Maternal Depression, But Not Exposure to SSRIs, Associated with Worse Executive Functioning in Children  

While we have considerable data on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, most of this research focuses on the risk of congenital malformations in exposed children.  We have far less information regarding the long-term effects of SSRI antidepressants on neurodevelopmental outcomes in exposed children. A recent study looks at executive functioning… Read More »